Mastermind group types of non-coding variants together to provide a highly sensitive return of evidence. Articles with an exact nucleotide-level match are prioritized on the list and designated with a crosshairs/target symbol, shown below:
In a search for MYH7:F244sd, for example, there are multiple nucleotide-level changes that fall into this “sd” (splice donor) bucket, including: c.732+1G>A, c.732+1del, and c.732+2T>G. When a search is performed for MYH7:c.732+1del, articles are returned for the entire F244sd bucket, but exact matches are prioritized and designated with the crosshairs symbol. You can read more about non-coding variants in our blog post here.