Mastermind
Genomic Search Engine
The World’s Most Comprehensive Database of Genomic Evidence
SEARCH MASTERMIND
Mastermind uses AI-driven genomics to accelerate variant interpretation, providing immediate insight into the full text of millions of scientific articles. Mastermind prioritizes your search results by clinical relevance and finds what you are looking for 5-10 times faster.
MASTERMIND WILL…
REDUCE TURNAROUND TIME
Quickly identify and review the empirical evidence, clinically prioritized with insight into each article to speed variant interpretation
INCREASE DIAGNOSTIC YIELD
Mastermind has 100X more genomic evidence and 50X more variants than other sources to help you find relevant articles and upgrade VUS calls
ACCELERATE THROUGHPUT
Scale your caseload and reduce the risk of missing a patient diagnosis —save 60-90 minutes per VUS search on average with Mastermind
LATEST WEBINAR: Using Mastermind’s New ClinVar Integration to Accelerate Clinical Diagnoses

Rady Children’s Institute for Genomic Medicine uses Mastermind
Read the inspiring story of how this world-class institute used Mastermind to make a life-changing diagnosis for a sick newborn.
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HOW DOES MASTERMIND COMPARE?
A Side-by-Side Summary
Mastermind | HGMD | ClinVar | |
---|---|---|---|
Genes | 19,340 | 15,493 | 16,879 |
Variants | 22,632,323 | 410,743 | 1,669,429 |
Germline Variants | YES | YES | YES |
Somatic Variants | YES | NO | YES |
Journals | 35,876 | 3,100 | 3,702 |
Full-Text Articles Indexed | 9,047,466 | 72,987 | 105,450 |
Supplemental Datasets Indexed | 3,166,515 | N/A | N/A |
Update Schedule | Weekly | Quarterly | Weekly |
Free Version Content | Up to Date | 3 Years Old | Up to Date |
Interpretation Criteria | ACMG/AMP | Own Criteria | ACMG/AMP |