About Genomenon

Powering Precision Medicine with Genomics


Genomenon is a genomic health IT company that keeps pace with the constant advancements made in genomics and connects that research to patient DNA to help diagnose and treat patients with rare genetic diseases and cancer.

The Mastermind Genomic Search Engine is used by hundreds of genetic labs worldwide to accelerate diagnosis, increase diagnostic yield, and assure repeatability in reporting genetic testing results.

Mastermind Genomic Landscapes inform pharmaceutical and bio-pharma companies on precision medicine development, deliver genomic biomarkers for clinical trial target selection, and support CDx regulatory submissions with empirical evidence. Genomenon was named 2020 Global Company of the Year in Clinical Genomics Interpretation by Frost & Sullivan.


Genomenon means “born out of need” in ancient Greek, which perfectly describes Genomenon’s beginnings.

In his clinical practice and genomic research, co-founder Dr. Mark Kiel was frustrated with the painfully slow and time-consuming process of manual curation. Interpretation of genomic data resulting from next-generation DNA sequencing (NGS) was inefficient and error-prone due to the manual effort required to search and analyze the rapidly growing body of medical literature for disease-related genes and variants.

Genomenon was founded to address this pressing need for faster, more comprehensive variant interpretation by combining expert curation with unique machine learning methods designed to keep up with the pace of new publications and present the most relevant information to researchers.

Mark found like-minded experts dedicated to connecting patient DNA data with the billions of dollars worth of medical research that was previously impossible to organize at scale, and too challenging to interpret quickly and accurately for clinical genomics.

The Genomenon team built the Mastermind Genomic Search Engine, which contains all the disease-gene-variant-phenotype-therapy relationships found across the scientific literature. The technology developed to accomplish this feat is revolutionizing the way genetic and cancer diagnoses and discoveries are made. Mastermind makes it easy to get rapid insight into relevant literature for clinical decision-making, genomic research, and pharmaceutical drug discovery.

Today, co-founders Kiel and Steve Schwartz continue to drive the scientific and technological development of Mastermind, which now empowers scientists and researchers at pharmaceutical companies, clinical labs, and universities to more thoroughly understand diseases at a molecular level. Thousands of doctors in over 100 countries are using Mastermind to rapidly connect their patient’s variants with the published genomic research to more effectively treat cancer patients and diagnose babies with rare diseases.

Genomenon is headquartered in Ann Arbor, Michigan.


Meet The Team

Mike Klein
Mike Klein CEO

With over 25 years of developing, building and growing 4 different high-tech companies, Mike raised over $50M in capital and had several successful investor exits.

Mark J. Kiel, MD, PhD
Mark J. Kiel, MD, PhD CSO & Co-Founder

Mark has extensive experience in genome-sequencing and clinical data analysis underlying the vision and technology driving the Genomenon suite of software tools.

Sean Kearney
Sean Kearney CFO

Always seeking opportunities for growth, Sean has spent his career investing in and scaling innovative platforms in genomics, telemedicine and healthcare delivery.

Sam Globus, PhD
Sam Globus, PhD COO

Sam brings a wealth of experience in genomic product development and operations to the team, and manages the rapid growth of our data science and variant curation work.

Brittnee Jones, PhD
Brittnee Jones, PhD VP, Product Management & Customer Success

Brittnee has spent over a decade building and leading customer success teams across the NGS space, ensuring rapid product adaption and maximal value for customers.

Candace Chapman
Candace Chapman VP, Marketing

Candace has 25 years experience in enterprise and high-tech marketing and brings both strategic leadership and tactical execution to the team.

Colleen McMillen
Colleen McMillen VP, Marketing

Colleen is an accomplished communications and marketing executive in the health space with more than two decades of experience delivering high-impact positioning for products, organizations and executive teams.

Arslan Berbic
Arslan Berbic VP, Business Development

As CEO of Boston Genetics (now part of Genomenon) Arslan brings a deep understanding of building and managing meaningful customer relationships in the diagnostic lab domain.

Dave Anstey
Dave Anstey VP, Sales & Business Development

Dave has almost 30 years of experience selling scientific software with a track record of building successful sales teams and meaningful customer relationships.

Marc Fink, PhD
Marc Fink, PhD Director of Biological Data Science

Marc drives innovation with his bioinformatics, genetics, pharmacology, and data science expertise, gained from over 15 years in academia and genomic companies.

Ronda Bergman
Ronda Bergman Director of Engineering

Ronda has spent more than 20 years working in software development in a variety of roles, from strategy execution to building effective teams.

Steve Schwartz
Steve Schwartz Co-founder & Advisor

Steve has co-founded several successful web-based software start-ups. He brings to the team deep domain expertise and extensive start-up experience.

Kojo Elenitoba-Johnson, MD
Kojo Elenitoba-Johnson, MD CO-FOUNDER & ADVISOR

Kojo is the Director for Precision and Computational Diagnostics at University of Pennsylvania Perelman School of Medicine and President of the Association of Molecular Pathology.

Megan Lim, MD, PhD

Megan is the Director of the Hematopathology and Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania.

Every accolade is a testament to our team and our mission to make genomic information actionable

Careers at Genomenon 

Click on our current open positions to learn more and apply. 
Scientific Program Manager

We are looking for a Scientific Program Manager who will report directly to our Director of Genomic Curation to manage curation projects and customer engagements. These projects include but are not limited to the development of comprehensive, annotated databases of genetic variants for a particular disease/gene, and the development of patient-focused databases with detailed genotype and phenotype information. Apply here

Clinical Account Manager

An “A player” salesperson who is adept in all aspects of B2B sales with experience building a sales pipeline to successful close of business to achieve the company’s revenue goals. This position requires a sales-savvy, highly energetic person with experience in NGS and bioinformatics solution sales to help drive the company’s sales efforts. The key focus of this role is to sell into clinical genetics testing labs at both Hospitals and commercial organizations.  Apply here

Senior Product Manager Clinical and Pharma Genomic Solutions

We are seeking a remote-based Senior Product Manager to be responsible for the commercial objectives and success of Mastermind, the most Comprehensive Genomics Search Engine, at Genomenon. As a Senior Product Manager, you will play a crucial role in driving the development and launch of cutting-edge genomics solutions for clinical diagnostics labs and pharma that have a significant impact on patient care and drug development. Apply here.

Citing Mastermind

When citing use of the Mastermind Genomic Search Engine, use the following text: 

Mastermind Genomic Search Engine (https://www.genomenon.com/mastermind

Details on the Mastermind research paper published in November of 2020:

PubMed: https://pubmed.ncbi.nlm.nih.gov/33281875/
DOI: https://doi.org/10.3389/fgene.2020.577152
Citation: Chunn LM, Nefcy DC, Scouten RW, Tarpey RP, Chauhan G, Lim MS, Elenitoba-Johnson KSJ, Schwartz SA, Kiel MJ. Mastermind: A Comprehensive Genomic Association Search Engine for Empirical Evidence Curation and Genetic Variant Interpretation. Front Genet. 2020 Nov 13;11:577152. doi: 10.3389/fgene.2020.577152. PMID: 33281875; PMCID: PMC7691534.

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