About Genomenon

Powering Precision Medicine with Genomics


Genomenon is a genomic health IT company that keeps pace with the constant advancements made in genomics and connects that research to patient DNA to help diagnose and treat patients with rare genetic diseases and cancer.

The Mastermind Genomic Search Engine is used by hundreds of genetic labs worldwide to accelerate diagnosis, increase diagnostic yield, and assure repeatability in reporting genetic testing results.

Mastermind Genomic Landscapes inform pharmaceutical and bio-pharma companies on precision medicine development, deliver genomic biomarkers for clinical trial target selection, and support CDx regulatory submissions with empirical evidence. Genomenon was named 2020 Global Company of the Year in Clinical Genomics Interpretation by Frost & Sullivan.


Genomenon means “born out of need” in ancient Greek, which perfectly describes Genomenon’s beginnings.

In his clinical practice and genomic research, co-founder Dr. Mark Kiel was frustrated with the painfully slow and time-consuming process of manual curation. Interpretation of genomic data resulting from next-generation DNA sequencing (NGS) was inefficient and error-prone due to the manual effort required to search and analyze the rapidly growing body of medical literature for disease-related genes and variants.

Genomenon was founded to address this pressing need for faster, more comprehensive variant interpretation by combining expert curation with unique machine learning methods designed to keep up with the pace of new publications and present the most relevant information to researchers.

Mark found like-minded experts dedicated to connecting patient DNA data with the billions of dollars worth of medical research that was previously impossible to organize at scale, and too challenging to interpret quickly and accurately for clinical genomics.

The Genomenon team built the Mastermind Genomic Search Engine, which contains all the disease-gene-variant-phenotype-therapy relationships found across the scientific literature. The technology developed to accomplish this feat is revolutionizing the way genetic and cancer diagnoses and discoveries are made. Mastermind makes it easy to get rapid insight into relevant literature for clinical decision-making, genomic research, and pharmaceutical drug discovery.

Today, co-founders Kiel and Steve Schwartz continue to drive the scientific and technological development of Mastermind, which now empowers scientists and researchers at pharmaceutical companies, clinical labs, and universities to more thoroughly understand diseases at a molecular level. Thousands of doctors in over 100 countries are using Mastermind to rapidly connect their patient’s variants with the published genomic research to more effectively treat cancer patients and diagnose babies with rare diseases.

Genomenon is headquartered in Ann Arbor, Michigan.


Meet The Team

Mike Klein
Mike Klein CEO

With over 25 years of developing, building and growing 4 different high tech companies, Mike raised over $50M in capital and had several successful investor exits.

Mark J. Kiel MD, PhD
Mark J. Kiel MD, PhD CSO & Co-Founder

Mark has extensive experience in genome-sequencing and clinical data analysis underlying the vision and technology driving the Genomenon suite of software tools.

Steve Schwartz
Steve Schwartz CTO & Co-founder

Steve co-founded several successful web-based software start-ups. He brings to the team deep domain expertise and extensive start-up experience.

Dave Anstey
Dave Anstey VP, Sales & Business Development

Dave has over 22 years experience selling scientific software with a track record of building successful sales teams and meaningful customer relationships.

Candace Chapman
Candace Chapman Vice President of Marketing

Candace has 25 years experience in enterprise and high-tech marketing and brings both strategic leadership and tactical execution to the team.

Elizabeth Varga
Elizabeth Varga Director of Customer Success

An established clinician, researcher and academician in the field of hematology/oncology and germline genomics, Elizabeth leads our client development and product marketing strategies.

Lianna Cecil
Lianna Cecil Sr. Controller

Lianna’s experience includes over a decade working with start-ups and technology companies. She oversees all areas of finance, accounting and HR.

Kojo Elenitoba-Johnson, MD
Kojo Elenitoba-Johnson, MD Co-founder & Advisor

Kojo is the Director for Precision and Computational Diagnostics at University of Pennsylvania Perelman School of Medicine and President of the Association of Molecular Pathology.

Megan Lim, MD, PhD
Megan Lim, MD, PhD Co-Founder & Advisor

Megan is the Director of the Hematopathology and Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania.

Careers at Genomenon 

Click on our current open positions to learn more and apply. 
Senior Software Developer

We’re looking for a senior full-stack software developer who can take direction and run with it, building out new and existing products and features. This role will be involved in our entire stack, and will take ownership of the services they build. View Job

Inside Sales Specialist

We’re looking for an Inside Sales Specialist within the genomics and life sciences market to be responsible for coordinating commercial aspects of our customer relationships including sales prospecting for new clients, lead follow up and qualification, quotes, processing orders, and working closely with customers to understand their requirements.  View Job

Citing Mastermind

Mastermind is a vital source of genomic information for researchers. When citing the use of Mastermind, please use the following text:  Mastermind Genomic Search Engine (https://www.genomenon.com/mastermind

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