Revolutionizing the Way Genetic Discoveries Are Made

Empowering personalized medicine by simplifying genome interpretation.

More About


Interpretation of next-generation sequencing DNA data is frustratingly inefficient and error prone due to the time consuming, manual approach required to search and curate the rapidly growing body of medical literature for disease-related genes and variants.

Genomenon has replaced the manual search process in gene and variant interpretation with a genomic search engine and database of all the disease-gene-variant relationships found in the full text of the scientific literature. Our technology is revolutionizing the way genetic diagnoses and discoveries are made by making it easier to get rapid insight into prioritized, clinically relevant literature for both clinical decision making and research projects.

We started with all 30 million titles and abstracts from PubMed to find all the scientific articles with any genomic content. From there, we have indexed the full text of almost six million genomic articles to create Mastermind, a comprehensive genomic search engine that enables pathologists and geneticists to quickly and accurately curate disease-causing genes and variants from patients’ DNA datasets.

With a comprehensive genomic data set and deep insight into all of the genomic literature, we are able to provide some fascinating results – from accelerated gene and variant curation for clinicians – to evidence-based panel design – to biomarker candidates backed by literature citations for co-diagnostics and clinical trials.


Meet The Team

Mike Klein
Mike Klein CEO

With over 25 years of developing, building and growing 4 different high tech companies, Mike raised over $50M in capital and had several successful investor exits.

Mark J. Kiel MD, PhD
Mark J. Kiel MD, PhD CSO & Co-Founder

Mark has extensive experience in genome-sequencing and clinical data analysis underlying the vision and technology driving the Genomenon suite of software tools.

Steve Schwartz
Steve Schwartz CTO & Co-founder

Steve co-founded several successful web-based software start-ups. He brings to the team deep domain expertise and extensive start-up experience.

Dave Anstey
Dave Anstey VP, Sales & Business Development

Dave has been in the business of science for 22+ years and spent the majority of that time selling scientific software. He has a long track record of building successful sales teams and meaningful customer relationships.

Candace Chapman
Candace Chapman Director of Marketing

Candace has 25 years experience in marketing and communications for enterprise B2C and high-tech B2B, and brings both strategic leadership and tactical execution to the team.

Colleen Spencer
Colleen Spencer CFO, CPA, MBA

As CFO, Colleen has guided over a half-dozen bio-tech startups through different stages of financing and investor exits.

Kojo Elenitoba-Johnson, MD
Kojo Elenitoba-Johnson, MD Co-founder & Advisor

Kojo is the Director for Precision and Computational Diagnostics at University of Pennsylvania Perelman School of Medicine and President of the Association of Molecular Pathology.

Megan Lim, MD, PhD
Megan Lim, MD, PhD Co-Founder & Advisor

Megan is the Director of the Hematopathology and Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania.

Careers at Genomenon 

Click on our current open positions to learn more and apply. 
Account Manager

This position will be a key contributor to the sales team for Genomenon to achieve our revenue growth goals. This full-time position requires a sales-savvy, highly energetic person with experience in NGS and bioinformatics solution sales to help drive the company’s sales efforts. Initially, this role will be an individual contributor position reporting directly to the VP of Sales and Business Development. View Job.

Field Application Scientist

The Field Applications Scientist is responsible for ensuring the successful implementation and support of Genomenon’s solutions within clinical labs and the pharmaceutical and biotechnology industries. The role supports sales team to help determine key target accounts and strategies to technically win sales opportunities. This role may also be actively involved in customer-facing bioinformatics projects as they arise. View Job. 

Senior Software Developer

We’re looking for a senior full-stack software developer who can take direction and run with it, building out new and existing products and features. This role will be involved in our entire stack, and will take ownership of the services they build.

You’ll be working directly with our CTO, who built several startups (the last of which was acquired by, and who authors and contributes to many open source projects, including as a member of the Ruby on Rails core team. You’ll also be working with a team of 3 other developers, who are even smarter than the CTO! View Job.

Inside Sales Specialist

We’re looking for an Inside Sales Specialist to be responsible for coordinating commercial aspects of our customer relationships including sales prospecting for new clients, lead follow up and qualification, quotes, processing orders, and working closely with customers to understand their requirements. View Job.

Citing Mastermind

Mastermind is a vital source of genomic information for researchers. When citing the use of Mastermind, please use the following text:  Mastermind Genomic Search Engine (

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