Genomenon is committed to advancing genomic intelligence by continuously aligning its platform with the evolving needs of researchers, clinicians, and diagnostic professionals. As part of this mission, the company is introducing a strategic enhancement to the Mastermind experience: the transition from Mastermind Basic to the newly developed solution, Mastermind CORE, effective May 15th.
Since its inception, Mastermind Basic has supported broad access to variant-level data, helping users bridge the gap between the published literature and genomic interpretation.
Mastermind CORE introduces a more advanced feature set, based on the functionality of the premium Mastermind PRO platform, and applies it to a curated set of clinically significant genes. This delivers a powerful, focused research tool and serves as a gateway to the full Mastermind ecosystem.
Mastermind CORE Overview
Mastermind CORE enables users to experience the features typically available only through PRO access. With CORE, users benefit from:
- Expert-curated variant insights for high-priority genes
- Gene–disease relationship data essential for diagnostic precision
- Advanced filters to refine variant queries by mechanism, classification, or relevance
- Indexed literature supporting copy number variation (CNV) searches
- Deeper clinical context from expertly curated findings
This streamlined access allows the research and clinical communities to engage with Mastermind’s powerful infrastructure in a way that is structured, scalable, and directly aligned with real-world workflows.
Unlocking the Full Power of Mastermind with PRO
Mastermind CORE equips users with curated insights across key genes. However, many clinical and research applications demand greater depth, wider coverage, and expanded flexibility. Mastermind PRO is built to deliver exactly that.
PRO users benefit from:
- Access to over 19,000 genes and 27 million variants
- Over 9,000 gene–disease relationships spanning more than 6,500 genes
- Indexed, searchable content from 10 million full-text articles and 3.5 million supplemental datasets
- Comprehensive variant coverage for ACMG secondary findings, hereditary cancer, cardiovascular panels, and more
Mastermind PRO is designed to meet the demands of high-throughput clinical labs, genomic researchers, and precision medicine programs — providing the depth and scalability needed to drive impactful genomic interpretation.
Those interested in exploring full PRO access — whether for individual use, institutional licenses, or team-wide implementation — are encouraged to schedule a personalized discovery session. Genomenon offers flexible licensing plans and guided walkthroughs tailored to specific organizational needs.
For additional information, the support team is available at support@genomenon.com.
Transition Timeline and Support
Starting May 15th, all existing Mastermind Basic accounts will automatically migrate to Mastermind CORE. While this change will adjust how users access data, Genomenon is committed to supporting the community throughout the transition.
Genomenon extends its gratitude to the entire Mastermind community for their continued trust and engagement. This transition marks an exciting new chapter — one focused on delivering deeper insight, broader access, and smarter solutions for genomic discovery.
