Mastermind Variant Interpretation Cards


Use Mastermind Variant Interpretation Cards to learn the ACMG Variant Interpretation framework and organize your variant interpretation activities


Download Cards PDF

Mastermind Variant Interpretation Cards
ACMG Variant Interpretation Cards
download your deck

Variant Interpretation Cards


Mastermind Variant Interpretation Cards

Deck Contents


10 Overview Cards

Overview Cards explain the various categories of criteria for interpretation of pathogenic or benign sequence variants (e.g. Pathogenic – Strong Evidence or PS)

Deck Contents



5 Scoring Cards

Scoring Cards detail the rules for combining criteria to classify sequence variants (e.g. Likely Pathogenic)

Deck Contents



5 Workflow Cards

Workflow Cards describe a proposed process for assessing the pathogenicity of a variant based on the various sources of data (e.g. Literature)

Deck Contents



28 Criteria Cards

Criteria Cards detail the features of each criterion for determining pathogenicity or benignness of a variant (e.g. PP3 Predicted Damaging)

Deck Contents

The World’s Most Comprehensive Source of Genomic Evidence


The World’s Most Comprehensive Source of Genomic Evidence

Mastermind accelerates variant interpretation with immediate insight into the full text of millions of scientific articles. Prioritize your search results by clinical relevance and find what you are looking for 5-10 times faster


CREATE YOUR FREE ACCOUNT