Simplify your ACMG variant classification using the Mastermind Genomic Search Engine

THE WORLD’S MOST COMPREHENSIVE SOURCE OF GENOMIC EVIDENCE

Mastermind Genomic Search Engine


Mastermind Genomic Search Engine
FASTEST

Find all relevant articles for your specific search criteria, covering every gene, variant, copy number variation (CNV), disease, phenotype, therapy, and categorical keyword.

SMARTEST

Updated weekly, you can find hidden data and prioritize your results with intelligent tools that bring the most relevant articles to the top for review.

MOST COMPREHENSIVE

Search beyond title and abstract into the complete text of every published genomic paper, including supplemental data.

Plans to fit your needs.

Gain immediate insight into millions of full text scientific articles with Mastermind. Whether you’re an academic, or part of a global genetics lab, we’ve got solutions for everyone.


MASTERMIND BASIC EDITION

Ideal for students and always free. Start with a complimentary trial of Mastermind Professional Edition. No credit card required and we’ll email the details to get started.

MASTERMIND PROFESSIONAL EDITION

Dive deeper into the published genomic literature with enhanced features including ACMG/AMP classification, supplemental datasets, CNVs, creating alerts and more.

Plans to fit your needs.
“Using Mastermind enhances our ability to provide clinicians at the bedside with important relevant information about known treatments and interventions.”
Stephen Kingsmore circle 500x500-01
Stephen Kingsmore, MD, DSc | President and CEO
Rady Children’s Institute for Genomic Medicine

Mastermind Explores Genomic Associations

Users can find, connect, explore, and understand the links between genomic concepts of interest in Mastermind’s intuitive literature search interface.


Identify every Genomic Association in the medical evidence

Draw informative connections between genomic concepts

Mastermind Explores Genomic Associations

HOW DOES MASTERMIND COMPARE?


A Side-by-Side Summary

In just 3 years, Mastermind surpassed the two primary sources of genomic literature, and we continue to add new data weekly! Here is a snapshot comparison.

 MastermindHGMDClinVar
Genes19,32014,47011,648
Variants
19,967,652377,5101,148,026
Germline VariantsYESYESYES
Somatic VariantsYESNOYES
Journals35,3543,1003,450
Full-Text Articles Indexed8,781,95372,98790,481
Supplemental Datasets Indexed3,062,690N/AN/A
Update ScheduleWeeklyQuarterlyWeekly
Free Version ContentUp to Date3 Years OldUp to Date
Interpretation CriteriaACMG/AMPOwn CriteriaACMG/AMP

Sources:
http://www.hgmd.cf.ac.uk/ac/stats.php
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429360/
https://www.oncokb.org/
https://cancer.sanger.ac.uk/cosmic/curation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323903/
https://www.ncbi.nlm.nih.gov/clinvar/submitters/
ftp://ftp.ncbi.nlm.nih.gov/pub/clinvar/tab_delimited/
https://www.qiagenbioinformatics.com/products/human-gene-mutation-database/1673-2/

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