Mastermind
Genomic Search Engine

The World’s Most Comprehensive Database of Genomic Literature



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Mastermind uses AI-driven genomics to accelerate variant interpretation, providing immediate insight into the full text of millions of scientific articles. Mastermind prioritizes your search results by clinical relevance and finds what you are looking for 5-10 times faster.

MASTERMIND IS…


<strong>FASTER</strong>

FASTER

Quickly find all relevant articles for your specific search criteria, covering every disease, therapy, phenotype, gene, and variant.

<strong>SMARTER</strong>

SMARTER

Find hidden data and prioritize your results with intelligent tools that bring the most relevant articles to the top for review.

<strong>MORE COMPREHENSIVE</strong>

MORE COMPREHENSIVE

Search beyond title and abstract into the complete text of every published genomic paper, including supplemental data.

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Rady Children’s Institute for Genomic Medicine uses Mastermind

Read the inspiring story of how this world-class institute used Mastermind to make a life-changing diagnosis for a sick newborn.


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Mastermind Explores Genomic Associations


Mastermind identifies every Genomic Association in the medical evidence, drawing informative connections between genes, variants, diseases, phenotypes, therapies, copy number variations (CNVs), and categorical keywords to inform both clinical care and drug discovery. Users can find, connect, explore, and understand the links between genomic concepts of interest in Mastermind’s intuitive literature search interface.

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HOW DOES MASTERMIND COMPARE?


A Side-by-Side Summary

In just 3 years, Mastermind surpassed the two primary sources of genomic literature, and we continue to add new data weekly! Here is a snapshot comparison.

 MastermindHGMDClinVarCOSMIC
Genes19,45511,32011,199719
Variants
7,018,831298,409846,360N/A
Germline VariantsYESYESYESNO
Somatic VariantsYESNOYESYES
Journals33,7203,1002,748N/A
Full-Text Articles Indexed7,999,33572,98778,712N/A
Supplemental Datasets Indexed2,865,66029,000N/AN/A
Update ScheduleWeeklyQuarterlyWeeklyQuarterly
Free Version ContentUp to Date4 Years OldUp to DateUp to Date
Interpretation CriteriaACMG/AMPOwn CriteriaACMG/AMPAMP

Sources:
http://www.hgmd.cf.ac.uk/ac/stats.php
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429360/
https://www.oncokb.org/
https://cancer.sanger.ac.uk/cosmic/curation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323903/
https://www.ncbi.nlm.nih.gov/clinvar/submitters/
ftp://ftp.ncbi.nlm.nih.gov/pub/clinvar/tab_delimited/
https://www.qiagenbioinformatics.com/products/human-gene-mutation-database/1673-2/

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