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Swift Biosciences and Genomenon Announce Partnership to Accelerate Biomarker Selection for Targeted NGS Panels

Swift Biosciences and Genomenon Announce Partnership to Accelerate Biomarker Selection for Targeted NGS Panels

Two Ann Arbor biotech companies provide translational researchers a faster, more comprehensive way to design Accel-Amplicon panels for variant discovery and screening studies

ANN ARBOR, Michigan – May 23, 2018 – Swift Biosciences—the NGS Library Prep company—and Genomenon—the leading genomic literature search engine company—announced today a new partnership to revolutionize the design of targeted gene sequencing panels for precision medicine initiatives.

Genomenon and Swift will co-market solutions in an integrated offering to make it easier to construct, validate and implement custom NGS assays as a follow-up to whole genome or exome sequencing studies, and dive deep into specific biological pathways. Together, these companies will empower researchers to quickly identify and elucidate mechanisms underlying genetic disease through a targeted sequencing approach, without the need for deep expertise in target curation and prior NGS panel development experience.

"Identifying biomarkers and designing targeted gene sequencing panels has traditionally been a time-consuming process” said Mike Klein, CEO of Genomenon. “Researchers can significantly shorten their experiment cycle times by working with Genomenon and Swift to select and design their targeted sequencing panels.”

Genomenon identifies biomarker targets associated with diseases by applying automated machine learning algorithms to its Mastermind Genomic Search Engine to objectively correlate genes and genetic variants with the quality and frequency of citations from the scientific literature. This approach produces a list of candidate biomarkers associated with a specific disease with reference citations for each biomarker-disease association. The Genomenon team then curates the biomarkers based on the strength and quality of the scientific evidence found in the literature and delivers a set of prioritized candidates for downstream panel design.

Once the list is identified, Swift builds and validates highly informative Accel-AmpliconCustom NGS Panels to deeply sequence targeted gene regions. Swift’s technology combines a two-hour, single-tube workflow with highly multiplexed, targeted PCR libraries that are compatible with both Illumina® and Ion Torrent™ sequencing platforms.The unique assay format is also compatible with most sample types, including limited or degraded samples such as FFPE and cfDNA samples.

Genomenon and Swift, both based in Ann Arbor, bring together unique strengths which enable more applications such as fine mapping, variant discovery and screening, postGWAS replication, drug target discovery, clinical trial management and monitoring therapeutic efficacy.

“With next generation sequencing becoming more widely adopted, we had to rethink how we enable Amplicon panel design and make it more accessible to the broader translational community,” said Candia L. Brown, Swift’s vice president of marketing. “We’re excited to partner with Genomenon to remove major bottlenecks and accelerate targeted panels for precision medicine efforts.”

About
Genomenon

Genomenon is a leading genomic intelligence company transforming patient care by uncovering the genomic drivers of genetic disease and cancer. By combining the power of AI built on the world’s premier genomic data set with genomic expertise, the company simplifies complex genetic data into actionable insights. Genomenon's integrated software, data, and services solutions empower clients with advanced patient diagnosis and precision medicine development.

About
Swift Biosciences

Swift Biosciences is the NGS Library Prep company. Based in Ann Arbor, Michigan, the company develops novel library preparation solutions for emerging applications based on next-generation sequencing, including whole genome sequencing, targeted DNA sequencing, and epigenetic analysis. Swift Biosciences’ products are designed to help customers analyze challenging biological samples faster, easier, and with greater sensitivity and accuracy, while being compatible with leading instrumentation. Swift Biosciences is the first company to offer library preparation solutions on all three major sequencing platforms, including Pacific Biosciences®, Illumina® and Ion Torrent™.

The company opened its doors in February 2010, and its product development enables new applications in multiple industries, including agrigenomics, pharmaceutical, academic, biotechnology, and oncology research fields.

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