How does Genomenon select a canonical transcript when curating literature?

Genomenon utilizes RefSeq transcripts in order to identify and define cDNA and protein variants. Prior to curation, our team reviews the canonical RefSeq transcript as noted in UniProt, as well as the MANE select transcript. In situations where the canonical transcripts differ, our team assesses the potential options in choosing a canonical transcript. Depending on how that search is performed, a user may be redirected to the curated data for the same variant on our canonical transcript.