< Resources


Mastermind Variant Interpretation Cards

Use Mastermind Variant Interpretation Cards to learn the ACMG Variant Interpretation framework and organize your variant interpretation activities.

Submit the form to download your deck:

Deck Contents
10 Overview Cards

Overview Cards explain the various categories of criteria for interpretation of pathogenic or benign sequence variants (e.g. Pathogenic – Strong Evidence or PS)

5 Scoring Cards

Scoring Cards detail the rules for combining criteria to classify sequence variants (e.g. Likely Pathogenic)

5 Workflow Cards

Workflow Cards describe a proposed process for assessing the pathogenicity of a variant based on the various sources of data (e.g. Literature)

28 Criteria Cards

Criteria Cards detail the features of each criterion for determining pathogenicity or benignness of a variant (e.g. PP3 Predicted Damaging)

The World’s Most Comprehensive Source of Genomic Evidence

Mastermind accelerates variant interpretation with immediate insight into the full text of millions of scientific articles. Prioritize your search results by clinical relevance and find what you are looking for 5-10 times faster

Create your free account
The Most Comprehensive Source of Curated Genomic Evidence + Scientific Experts

We help provide insights into key genetic drivers of diseases and relevant biomarkers. By working together to understand this data, we enable scientists and researchers to make more informed decisions on programs of interest. To learn more about how we can partner together to find your genomic variant solutions, we invite you to click on the link below.

Contact Us
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.