Mastermind Video Tutorials
Informative Walkthroughs of the Mastermind Genomic Search Engine
GETTING STARTED
How to sign up for Mastermind and create your user account
LAUNCHING A SEARCH
This quick tutorial shows you to start searching in Mastermind.
MASTERMIND GENOMIC SEARCH ENGINE
Learn about Mastermind’s AI-driven technology with several use cases
Disease-Specific Curated Content
DISEASE-SPECIFIC CURATED CONTENT
Essential information on disease variants, diagnosis, and clinical trials
Mastermind Professional Edition Search Examples
ACMG/AMP FILTERING AND SUPPLEMENTAL DATA
What do we know about genetic variants inherited as germline mutations?
VIEWING ALTERNATIVE NOMENCLATURES
Is an intronic variant in a particular gene novel?
PHENOTYPE, GENE, AND VARIANT
How are specific genes and phenotypes associated?
FUSION GENES
Which fusion genes are associated with somatic cancers?
SEARCHING GENES BY PHENOTYPE
Which genes are associated with a specific phenotype?
THERAPY, DISEASE, AND GENES
Which therapies are currently used for genetically-driven diseases?
EXPLORING NOVEL VARIANTS
What do I do if a variant can’t be found in Mastermind?
How can I create alerts for me and my team?
LOSS OF FUNCTION VARIANTS AND PHENOTYPE FILTERING
Which loss-of-function mutations in a gene are associated with a specific phenotype?
Copy Number Variation (CNV) Search Examples
CNVs: Genomic Coordinates and Phenotypes
CNVs: Intragenic CNVs and Boolean Searches for Gains/Losses
CNVs: Cytobands and Exploring the CNV Diagram
CNVs: Array Nomenclature and Sorting