Discovering High Yield Disease-Gene-Variant Associations
A novel and highly useful feature of the Mastermind software is the Recurrent Terms category. This feature comprises a set of key terms that are created in real-time for a set of filtered articles on Mastermind’s Association Pages. These key terms are identified because they appear recurrently throughout the selected articles at a frequency much higher than in unrelated articles. These key terms can themselves be used to filter the articles to identify the most high-yield content for a given Disease-Gene or Disease-Gene-Variant association.
Variant Search Gene Nomenclature in Mastermind
The myriad ways authors can describe genetic variants poses a challenge for devising effective ways to search for genomic publications likely to be useful for making diagnostic decisions. In this blog post, we clarify how Mastermind continues to address this issue of diversity of variant nomenclature to maximize the sensitivity of the variant search space and to provide our users with the best opportunity to identify high-yield content to inform their curation efforts.
Mastermind API Supports Automated Variant Curation Workflows
Mastermind supports the ability to generate queries via API calls to take users to selected content in Mastermind based on disease, gene, variant and PubMed identification number (PMID). This post details how to make an API call for disease, gene, variant and/or specific article.
Automating Genetic Literature Searches in Excel
Mastermind supports the ability to generate queries based on URL variables, which can be easily manipulated in spreadsheet software such as Microsoft Excel. This post detail how to programmatically generate URLS in a spreadsheet software.