Genomic Variant Curation: “The Power of Zero”

As a parent, sometimes the most powerful answer you can give your children is “no”.
Once they know where the boundaries are, they just might stop trying to navigate the gray area to find loopholes. The same can be said for genomic variant curation.
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Mastermind vs. Manually Curated Databases: Head-to-Head Comparison with COSMIC Variant Database

Mastermind’s Genomic Search Engine uncovers 594% More Articles per Variant and 63% More Variants per Gene in a head-to-head test against COSMIC variant database. The Mastermind Genomic Search Engine has a number of meaningful advantages over the Catalogue of Somatic Mutations in Cancer (COSMIC) as a tool for searching genomic evidence, reducing the amount of time required to curate variants and resulting in fewer missed articles containing evidence for the variant.
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Mastermind Genomic Search Engine Updates – March 2018

Thank you for being a part of the Mastermind Community. In addition to adding up to 20,000 new articles a week to our Genomic Search Engine, we are committed to continuously improving the Mastermind search algorithms and product capabilities.

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Google Scholar vs. Mastermind: Variant Interpretation Comparison

In the test described below, the Mastermind Genomic Search Engine was found to have several meaningful advantages over Google Scholar as a tool for searching genomic evidence, reducing the amount of time required to curate a variant and resulting in fewer missed articles containing evidence for the variant. Users who searched Mastermind as part of this experiment felt more confident that they had found all of the relevant literature to form the most accurate diagnoses and treatment plans.

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